Expanded NI/+
All chromosomes and deletions/duplications >7 Mb.
Open informationWeeks 11–13+6
First-trimester ultrasound
This is a key examination for dating, early anatomy and screening information. It is not simply a scan to “see the baby”.
- Obstetric consultation
- Advanced ultrasound
- Laboratory and screening
- Late-pregnancy monitoring
- Nutrition
Complementary follow-upAskabide + Osakidetza · birth at the reference hospital
What is assessed
- Gestational age and biometry.
- Number of fetuses and, in multiple pregnancy, chorionicity/amnionicity.
- Cardiac activity and accessible early anatomy.
- Nuchal translucency and other protocol markers.
- Placenta, uterus and relevant structures.
- Uterine artery Doppler when included in preeclampsia screening.
Screening is not diagnosis
Ultrasound may be combined with maternal age and biochemical markers to estimate risk of selected chromosome conditions. High- or low-risk results are not diagnostic confirmation.
NI/+ adds another screening approach through cell-free DNA in maternal blood, but it also remains a screening test.
Preeclampsia screening
How maternal factors and measurements are combined.
Open informationIf the examination cannot be completed
Fetal position, gestational age or imaging conditions may prevent a particular measurement. Movement, waiting or a partial repeat may be recommended without this necessarily indicating an anomaly.
The next major milestone
Anomaly scan
Detailed anatomical assessment around week 20.
Open informationClinical sources
General information only. It does not replace an individual medical assessment or recommendation.
Reviewed 19 August 2026